Senator McCain spoke out today against "big government" taking over America's health care.

"We must move away from a system that is fragmented and pays for expensive procedures toward one where a family has a medical home, providers coordinate their efforts and take advantage of technology to do so cheaply, and where the focus is on affordable quality outcomes," McCain said during a speech at the Miami Children's Hospital in Miami, Florida.

Calling the more than $2 trillion the nation spends annually on health care "staggering," McCain challenged doctors, hospitals, drug manufactures and insurance providers to do a better job of holding down costs.

"These costs are a threat to the ability of Americans to have health insurance, the gateway to better health care. These costs are a threat as well to the ability of American workers to build a better life," he said. "Rising costs of health care and health insurance have squeezed the wages that workers earn and consumed the budgets of their families."

The presumptive Republican presidential nominee rejected a single-payer system to lower health care costs, saying similar systems in other countries force "real people [to] pay a deeper cost through long waits for treatment or settling for care that does not take advantage of the latest medical science."

Instead, McCain promised to work to transform the health care system by putting "families in charge."

"We must reform the health care system to make it responsive to the needs of American families -- not the government, not the insurance companies, not tort lawyers, not even the doctors and hospitals," McCain said.

The solution, McCain said, "isn't a one-size-fits-all-big government takeover" but "with the American people themselves."